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KMID : 0363319890100010039
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Journal of Korean Oriental Internal Medicine
1989 Volume.10 No. 1 p.39 ~ p.52
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Experimental Studies on the Effiency of Sagantang
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Lee Won-Ik
Lee Won-Chul
Bae Hyung-Sup
Goo Bon-Hong
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Abstract
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The present investigation was undertaken to confirm of clinical effects of Sagnating. So, experimental studies were done, especially, to ascertain whether Sagantang had pharmacological effect of analgesia, antipyresis, diuresis and decreasing blood pressure and so on.
The results of the studies were obtained as follows:
1. The analgesic effects of Sagantang were obtained in mice.
2. Sagantang prolonged the duration of hypnosis which is induced thiopental-Na in mice, but it was not effective in rotor rod method.
3. Antipyretic effect of Sagantang was known on the typhoid vaccine induced fever in rats.
4. Sagantang inhibited automatic movement on the isolated ileum of mice, and antiacetylcholine effect and antibarium chloride effect of Sangantang were known on that.
5. Sangantang decreased blood pressure due to vasodilatation in anesthetized mice.
6. The effect of diuresis were noted in mice.
According to the above results, clinical effects of Sagantang on oriental medical references were similar to the actual experimental results.
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